Norclomipramine

Norclomipramine, also known as N-desmethylclomipramine and chlordesipramine, is the major active metabolite of the tricyclic antidepressant (TCA) clomipramine (Anafranil).[1]

Norclomipramine
Clinical data
Other namesN-Desmethylcomipramine; Chlordesipramine; 3-Chlorodesipramine
Identifiers
  • 3-(2-Chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.164.655
Chemical and physical data
FormulaC18H21ClN2
Molar mass300.83 g·mol−1
3D model (JSmol)
  • CNCCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl
  • InChI=1S/C18H21ClN2/c1-20-11-4-12-21-17-6-3-2-5-14(17)7-8-15-9-10-16(19)13-18(15)21/h2-3,5-6,9-10,13,20H,4,7-8,11-12H2,1H3
  • Key:VPIXQGUBUKFLRF-UHFFFAOYSA-N

References
  1. Lemke TL, Williams DA (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 605–. ISBN 978-1-60913-345-0.


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