Mitoguazone

Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy.[1]

Mitoguazone
Clinical data
Other names2-[[(1E)-1-(Diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine
ATC code
Identifiers
  • (2E,2'E)-2,2'-(1E,2E)-propane-1,2-diylidenedihydrazinecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.121.515
Chemical and physical data
FormulaC5H12N8
Molar mass184.207 g·mol−1
3D model (JSmol)
  • C\C(\C=N\NC(N)=N)=N/NC(N)=N
  • InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+ N
  • Key:PKDBCJSWQUOKDO-UHFFFAOYSA-M N
 NY (what is this?)  (verify)

References
  1. Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E (1989). "[Mitoguazone (methylglyoxal bis(guanylhydrazone))--its status and prospects]". Archiv Fur Geschwulstforschung (in German). 59 (2): 135–48. PMID 2655552.
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