KCNH8

KCNH8
Identifiers
Aliases	KCNH8, ELK, ELK1, Kv12.1, elk3, potassium voltage-gated channel subfamily H member 8
External IDs	OMIM: 608260 MGI: 2445160 HomoloGene: 14332 GeneCards: KCNH8
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	19,535,642 bp[1]
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)[2]
End	53,286,222 bp[2]
RNA expression pattern
	Top expressed in
	corpus callosum; ; Brodmann area 46; ; anterior pituitary; ; globus pallidus; ; brain; ; substantia nigra; ; amygdala; ; pituitary gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; phosphorelay sensor kinase activity; potassium channel activity; voltage-gated ion channel activity;
Cellular component	integral component of membrane; intracellular anatomical structure; membrane; integral component of plasma membrane; plasma membrane;
Biological process	phosphorelay signal transduction system; regulation of membrane potential; potassium ion transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; signal transduction; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	131096
	211468
	ENSG00000183960
	ENSMUSG00000035580
	Q96L42
	P59111
	NM_144633
	NM_001031811
	NP_653234
	NP_001026981
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene.[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5]

References

GRCh38: Ensembl release 89: ENSG00000183960 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000035580 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

Kv12.1+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
KCNH8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.