Hydroxyestrone diacetate

Hydroxyestrone diacetate (brand names Colpoginon, Colpormon, Hormobion, Hormocervix) (former developmental code name RD-310), or 16α-hydroxyestrone diacetate, also known as 3,16α-dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate, is a synthetic, steroidal estrogen which has been marketed in France, Spain, Brazil, and Argentina.[1][2] It is a derivative of 16α-hydroxyestrone with an acetate esters attached at the C3 and C16α positions.[1]

Hydroxyestrone diacetate
Clinical data
Trade namesColpoginon, Colpormon, Hormobion, Hormocervix
Other namesRD-310; 16α-Hydroxyestrone diacetate; 3,16α-Dihydroxyestra-1,3,5(10)-trien-17-one 3,16α-diacetate
Routes of
administration		By mouth
Drug classEstrogen; Estrogen ester
Identifiers
  • [(8R,9S,13S,14S,16R)-3-acetyloxy-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-16-yl] acetate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.013.634
Chemical and physical data
FormulaC22H26O5
Molar mass370.445 g·mol−1
3D model (JSmol)
  • CC(=O)OC1CC2C3CCC4=C(C3CCC2(C1=O)C)C=CC(=C4)OC(=O)C
  • InChI=1S/C22H26O5/c1-12(23)26-15-5-7-16-14(10-15)4-6-18-17(16)8-9-22(3)19(18)11-20(21(22)25)27-13(2)24/h5,7,10,17-20H,4,6,8-9,11H2,1-3H3/t17-,18-,19+,20-,22+/m1/s1
  • Key:QZQSENRWYLQIPC-JPVHLGFFSA-N

See also

References
  1. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 531–. ISBN 978-3-88763-075-1.
  2. Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. ISBN 978-3-527-30247-5.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.