Hydromadinone acetate

Hydromadinone acetate (developmental code name NSC-33170), also known as chloroacetoxyprogesterone (CAP), as well as 6α-chloro-17α-acetoxyprogesterone or 6α-chloro-17α-acetoxypregn-4-ene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.[1][2] It is the C17α acetate ester of hydromadinone, which, similarly, was never marketed.[1]

Hydromadinone acetate
Clinical data
Other namesNSC-33170; Chloroacetoxyprogesterone; CAP; 6α-Chloro-17α-acetoxyprogesterone; 6α-Chloro-17α-acetoxypregn-4-ene-3,20-dione
Drug classProgestogen; Progestogen ester
Identifiers
  • [(6S,8R,9S,10R,13S,14S,17R)-17-Acetyl-6-chloro-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.124.835
Chemical and physical data
FormulaC23H31ClO4
Molar mass406.95 g·mol−1
3D model (JSmol)
  • CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)Cl)C)OC(=O)C
  • InChI=1S/C23H31ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11,16-18,20H,5-10,12H2,1-4H3/t16-,17+,18+,20+,21-,22+,23+/m1/s1
  • Key:DCVGANSDLNPXGO-WXLIAARGSA-N

See also

References
  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 255–. ISBN 978-1-4757-2085-3.
  2. Negwer M, Scharnow H (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3723. ISBN 978-3-527-30247-5.



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