Atizoram

Atizoram (CP-80633) is a phosphodiesterase 4 inhibitor.[1]

Atizoram
Names
IUPAC name
5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydro-2(1H)-pyrimidinone
Other names
CP-80633
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C18H24N2O3/c1-22-15-5-4-12(14-9-19-18(21)20-10-14)8-17(15)23-16-7-11-2-3-13(16)6-11/h4-5,8,11,13-14,16H,2-3,6-7,9-10H2,1H3,(H2,19,20,21)/t11-,13+,16+/m1/s1
    Key: LITNEAPWQHVPOK-FFSVYQOJSA-N
  • COC1=C(C=C(C=C1)C2CNC(=O)NC2)O[C@H]3C[C@@H]4CC[C@H]3C4
Properties
C18H24N2O3
Molar mass 316.401 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Wright, K. F.; Turner, C. R.; Jayasinghe-Beck, R.; Cohen, V. L.; Cheng, J. B.; Watson, J. W. (August 1997). "Differential in vivo and in vitro bronchorelaxant activities of CP-80,633, a selective phosphodiesterase 4 inhibitor". Can. J. Physiol. Pharmacol. 75 (8): 1001–8. doi:10.1139/y97-123. PMID 9360015.
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