Alpharetrovirus

Alpharetrovirus is a genus of the family Retroviridae. It has type C morphology. Members can cause sarcomas, other tumors, and anaemia of wild and domestic birds and also affect rats.

Alpharetrovirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Subfamily: Orthoretrovirinae
Genus: Alpharetrovirus
Species

Avian carcinoma Mill Hill virus 2
Avian leukosis virus
Avian myeloblastosis virus
Avian myelocytomatosis virus 29
Avian sarcoma virus CT10
Fujinami sarcoma virus
Rous sarcoma virus
UR2 sarcoma virus
Y73 sarcoma virus

Species include the Rous sarcoma virus, avian leukosis virus, and avian myeloblastosis virus (AMV[1]). Not all animals that can infect develop cancer. The tumor caused by the virus is usually in the form of lymphoma and leukemia. It occurs after a long and latent process. The tumor cells formed consist of a single progenitor cell and are clonal. However, infection from retroviruses does not directly produce tumors, but only placement and recombination events leading to tumor cell formation.

References
  1. Perbal, Bernard (2008). "Avian myeoloblastosis virus (AMV): only one side of the coin". Retrovirology. 5 (1): 49. doi:10.1186/1742-4690-5-49. Retrieved 5 October 2021.


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