TCTN3

Tectonic family member 3 is a protein in humans that is encoded by the TCTN3 gene. [5]

TCTN3
Identifiers
Aliases	TCTN3, C10orf61, JBTS18, OFD4, TECT3, tectonic family member 3
External IDs	OMIM: 613847 MGI: 1914840 HomoloGene: 9221 GeneCards: TCTN3
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.1 Start 95,659,823 bp[1] End 95,694,143 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 40,584,890 bp[2] End 40,600,677 bp[2]
RNA expression pattern Bgee Top expressed in corpus epididymis thyroid gland caput epididymis fallopian tube ovary islet of Langerhans retinal pigment epithelium left coronary artery More reference expression data BioGPS n/a
Orthologs
Species	Human	Mouse
Entrez	26123	67590
Ensembl	ENSG00000119977	ENSMUSG00000025008
UniProt	Q6NUS6	Q8R2Q6
RefSeq (mRNA)	NM_001143973 NM_015631	NM_026260 NM_001365072
RefSeq (protein)	NP_001137445 NP_056446	NP_080536 NP_001352001
Location (UCSC)	Chr 10: 95.66 – 95.69 Mb	Chr 19: 40.58 – 40.6 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Oral-facial-digital syndrome IV and Joubert syndrome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].