David Jack (pharmacologist)
Sir David Jack CBE FRS FRSE[1] (22 February 1924 – 8 November 2011[2][3]) was a Scottish pharmacologist and medicinal chemist who specialised in the development of drugs for treating asthma. He was head of research and development at Glaxo from 1978 until 1987.
| Sir David Jack | |
|---|---|
| .jpg.webp) | |
| Born | 22 February 1924 | 
| Died | 8 November 2011 (aged 87) | 
| Citizenship | British | 
| Alma mater | |
| Known for | Drug discovery and development | 
| Spouse(s) | Lydia Downie Brown (1952–2016) | 
| Awards | 
 | 
| Scientific career | |
| Fields | Pharmacology, Medicinal chemistry | 
| Institutions | Allen & Hanburys, Glaxo | 
| Doctoral advisor | Arnold Beckett | 
Early life and education
    
Jack was born the sixth and youngest child of a coal miner, in Markinch, Fife, Scotland.[4] He attended Buckhaven High School before turning down a place at Edinburgh University to become an apprentice pharmacist. In 1944, having completed his apprenticeship, he began a BSc course in chemistry and pharmacy at the Royal Technical College, Glasgow. He won a number of undergraduate prizes and graduated with first class honours.[4]
Career
    
He turned down an offer to study for a doctorate and instead worked as an assistant lecturer at the University of Glasgow.[1][4]
In 1951 he joined the pharmaceutical company Glaxo Laboratories, moving to Smith Kline and French in 1953.[4] In 1961 he became director of research at Allen and Hanburys, a subsidiary of Glaxo, and served as Glaxo's research and development director from 1978 until his official retirement in 1987.[2]
Jack was known for heading a group which developed the following drugs:
- Beclometasone in 1962
- Salbutamol or Albuterol in 1966,
- Ranitidine in 1977,
- Sumatriptan in 1984,
- Salmeterol or serevent in 1985,
- Ondansetron in 1987,
- and Fluticasone propionate in 1993.
Honours
    
Jack was knighted for services to the pharmaceutical industry in 1993.[4]
In 1987, he was awarded an Honorary Degree (Doctor of Science) by the University of Bath.[5]
References
    
- Breckenridge, S. Alasdair (2014). "Sir David Jack. 22 February 1924 -- 8 November 2011". Biographical Memoirs of Fellows of the Royal Society. 60: 249–260. doi:10.1098/rsbm.2014.0006.
- "Sir David Jack". The Daily Telegraph. 17 November 2011. Retrieved 25 November 2011.
- "Sir David Jack". The Herald. 19 November 2011.
- "Obituary, Sir David Jack". The Times. Retrieved 18 November 2011.
- "Honorary Graduates 1989 to present". bath.ac.uk. University of Bath. Retrieved 18 February 2012.
External links
    
- Last Word 25/11/2011 BBC Radio 4.
- Interviews with Sir David Jack CBE FRS FRSE. Oxford Brookes University Library Medical Sciences Video Archive
- David Jack on the History of Modern Biomedicine Research Group website