SMIM20

Small integral membrane protein (SMIM) 20 is a protein that in humans is encoded by the SMIM20 gene.[5] SMIM20 acts as a prohormone to the peptide hormone phoenixin which was discovered for the first time in 2013 in rodent sensory ganglia.[6]

SMIM20
Identifiers
Aliases	SMIM20, C4orf52, small integral membrane protein 20, MITRAC7, PNX
External IDs	OMIM: 617465 MGI: 1913528 HomoloGene: 82612 GeneCards: SMIM20
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p15.2 Start 25,861,830 bp[1] End 25,929,813 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 C1 Start 53,424,425 bp[2] End 53,435,882 bp[2]
RNA expression pattern Bgee Top expressed in Achilles tendon muscle of leg deltoid muscle gastrocnemius muscle biceps brachii quadriceps femoris muscle body of stomach vastus lateralis muscle nucleus accumbens More reference expression data BioGPS n/a
Gene ontology Molecular function GO:0001948 protein binding Cellular component membrane integral component of membrane mitochondrion mitochondrial inner membrane Biological process mitochondrial cytochrome c oxidase assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	389203	66278
Ensembl	ENSG00000250317	ENSMUSG00000061461
UniProt	Q8N5G0	D3Z7Q2
RefSeq (mRNA)	NM_001145432 NM_001394130	NM_001145433
RefSeq (protein)	NP_001138904	NP_001138905
Location (UCSC)	Chr 4: 25.86 – 25.93 Mb	Chr 5: 53.42 – 53.44 Mb
PubMed search	[3]	[4]
Wikidata
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