Megami Magazine was published on July 28, 1999 as a separate volume using the empty space left by the discontinuation of “Looker” which was published as an extra edition of the anime magazine "Animedia" by Gakken Kenkyusha (later Gakken Holdings). Initially it was released every odd month on the 28th,then from Vol. 4 (released on February 28, 2000), it switched to every even month of the 28th. Then from Vol. 6 (released on June 30, 2000), the release date was set to the 30th. The magazine became a monthly publication on the  29th of November 2000 with the release of an extra special edition issue known as: “Megami Magazine Special”, which was launched independently from the main issue of “Animedia” from Vol. 34 (in March 2003). At the beginning of the publication, it focused on so-called gal games, but has since shifted to an anime focus due to a surge in moe anime immediately after it became a monthly publication.

Immediately after the first issue, many minor works were discovered, and the magazine was one of the first to feature an article on “Cosmic Baton Girl Comet-san☆”, which was rarely featured in anime magazines. Back when the first issue came out, the price was 680 yen. However, it was sold at a premium price of 780 yen until around 2006. Then the regular price became 780 yen. As of today, in 2022, the prices have been raised to 1,500 yen (book version) / 1,263 yen (electronic book version). It’s unique because each issue is supplemented by more than 20 posters. As of July 2013, the number of works handled was over 1,000; large and small. The magazine is primarily for a male audience because, It prominently depicts female characters wearing unrealistic skimpy designs of swimsuits and underwear. It may also include bathing scenes that show semi-nudity of these fictional female characters.

Similar magazines with a concept centered on Moe anime have been published as extra editions and mooks by other companies, but both have been relatively short-lived. Until the April 2005 issue, there was a section introducing adult anime, which included scenes of female characters with their nipples exposed. Some works even had posters attached, however that section has been discontinued since. Adult games continued to be introduced, however no sexual scenes were shown. By the September issues 2008 release, the magazine had finally achieved a total of 100 issues. With the reorganization of the Gakken Group in October 2009, Gakken Publishing became the publisher. It celebrated its 10th anniversary of the first issue in the same year. Gakken Plus became the publisher since the December issue, after the merging of Gakken Publishing with Gakken Marketing and others. In April 2018, following "Animedia" and "Voice Actor Animedia", sales of the e-book version started along with "Otomedia". As of  February 1st 2020,the editing and publishing business was transferred from Gakken Plus to IID along with "Animedia". As a result, after the April issue of the same year (released on February 29), editing and publishing are done by IID, and released by Gakken Plus.

2006 (September 2005 - August 2006) 47,717

2007 (September 2006 - August 2007) 64,391

2008 (October 2007 - September 2008) 74,600

Number of copies sold (after April 2008) (Japan Magazine Publishers Association)

Along with the main Megami Magazine line, Gakken also publishes several other titles using the same name or content.

Claire Froebel (Voice actor: Reiko Takagi / character design: Masa Shiranagi. The name was decided on by public readers) who is the navigator of the reader's corner "MegaTen!" had appeared in the magazine's TV commercials aired in Magical Girl Lyrical Nanoha A's and became a de facto mascot character of the magazine.

On the introduction page of the program for anime broadcast, there was an error saying that  “Suite PreCure ♪” was broadcast on Sundays at 3:30 PM on the “Miyazaki Broadcasting Channel.” Somehow the error was there, even though “Suite PreCure ♪” was not released yet, when the broadcast schedule was published. In addition, there was a similar mistake in the previous program about the anime “Heart Catch PreCure!”. In addition, “Miyazaki Broadcasting” broadcast works from the same time slots 16 days later  (The delay was half a year, until mid-July of 2012. However, the delays were shortened because two episodes were broadcast together until mid-November of 2012. Then it was discontinued in March 2018.on Tuesday at 3:30 PM. It seems to have been a typographical error in the description of this time slot, but no one understands how the mistake went undiscovered for so long.

In commemoration of the 100th issue of the magazine in September 2008, the internet radio program “HAMIDASE! Megami Magazine RADIO!!” was broadcast in August the same year. From October 2009, regular broadcasting started on Radio Kansai and Nippon Cultural Broadcasting's digital radio "Cho! A & G +". The program was remastered to "Hamiraji!!" since April 2012, but it ended on October 4, 2015.

Details on the cover illustrations and extras included in individual magazines are shown in the following table.[5]

• Megami Bunko
• Anime magazine
• Animedia
• Voice actor Animedia -The composition of the magazine is based on this magazine.
• Daughter TYPE
• Moe
• Girl love

• Official site (in Japanese)
• Megami Magazine Editorial Department (@MegamiMAGAZINE) --Twitter