GNA14

GNA14
Identifiers
Aliases	GNA14, G protein subunit alpha 14, HG1I
External IDs	OMIM: 604397 MGI: 95769 HomoloGene: 68386 GeneCards: GNA14
Gene location (Human)
Chr.	Chromosome 9 (human)[1]
End	77,648,322 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	16,588,184 bp[2]
RNA expression pattern
	Top expressed in
	myometrium; ; smooth muscle tissue; ; thyroid gland; ; urinary bladder; ; adrenal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	guanyl nucleotide binding; nucleotide binding; GTP binding; GO:0001948 protein binding; metal ion binding; G protein-coupled receptor binding; GO:0006184 GTPase activity; signal transducer activity; G-protein beta/gamma-subunit complex binding;
Cellular component	plasma membrane; extracellular exosome; heterotrimeric G-protein complex;
Biological process	platelet activation; phospholipase C-activating dopamine receptor signaling pathway; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9630
	14675
	ENSG00000156049
	ENSMUSG00000024697
	O95837
	P30677
	NM_004297
	NM_008137
	NP_004288
	NP_032163
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-14 is a protein that in humans is encoded by the GNA14 gene.[5][6][7] G₁₄α is a member of the Gq alpha subunit family, and functions as a constituent of a heterotrimeric G protein in cell signal transduction.

References

GRCh38: Ensembl release 89: ENSG00000156049 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000024697 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Wilkie TM, Gilbert DJ, Olsen AS, Chen XN, Amatruda TT, Korenberg JR, Trask BJ, de Jong P, Reed RR, Simon MI, et al. (Jun 1993). "Evolution of the mammalian G protein alpha subunit multigene family". Nat Genet. 1 (2): 85–91. doi:10.1038/ng0592-85. PMID 1302014. S2CID 31888533.
"Entrez Gene: GNA14 G protein subunit alpha 14 [ Homo sapiens (human) ]". Retrieved 2019-07-25.
GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-14; GNA14 at OMIM. Retrieved JULY 25, 2019.

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