Alpha-guaiene synthase
Alpha-guaiene synthase (EC 4.2.3.87, PatTps177 (gene)) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, alpha-guaiene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate alpha-guaiene + diphosphate
| Alpha-guaiene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.87 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme requires Mg2+.
References
- Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M (October 2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Archives of Biochemistry and Biophysics. 454 (2): 123–36. doi:10.1016/j.abb.2006.08.006. PMID 16970904.
- Kumeta Y, Ito M (December 2010). "Characterization of delta-guaiene synthases from cultured cells of Aquilaria, responsible for the formation of the sesquiterpenes in agarwood". Plant Physiology. 154 (4): 1998–2007. doi:10.1104/pp.110.161828. PMC 2996018. PMID 20959422.
External links
- Alpha-guaiene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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